Hypopituitarism, Optic nerve hypoplasia and septo-optic dysplasia

The pituitary gland secretes a variety of important hormones. A child with Optic nerve hypoplasia/ septo-optic dysplasia/Hypopituitarism can be missing one or multiple pituitary hormones.  Some children are not missing any hormones.  Each potential hormone is listed below along with a description of symptoms associated with a deficiency of that hormone. 

Growth hormone: slow growth and short stature

Thyroid-stimulating hormone or TSH: This hormone controls production of thyroid hormone 

Gonadotropins (luteinizing hormone or LH and follicle-stimulating hormone or FSH): These hormones are important for the initiation of puberty.  

Adrenocorticotropic hormone (ACTH): This hormone stimulates the release of cortisol from the adrenal glands.  Cortisol is an important hormone when our bodies are in a state of stress.  

Anti-diuretic hormone (ADH): This hormone helps the kidneys concentrate urine when a child is dehydrated. 

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